Lilrb3 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comLilrb3 Polyclonal Antibody for Mouse(Mus musculus)

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Lilrb3 (Gene name),

Leukocyte immunoglobulin-like receptor subfamily B member 3 (Protein name ), LIRB3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Lilrb3(Pirb);

Protein name:

Leukocyte immunoglobulin-like receptor subfamily B member 3(LIR-3);

Alternative:

Paired immunoglobulin-like receptor B(PIR-B);Cell-surface glycoprotein p91;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with LYN, PTPN6/SHP-1 and PTPN11/SHP-2.

Function:

May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).

Subcellular Location:

Cell membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

841

Sequence:

50:

100:

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650:

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841:

TLRQGAAASP | LSQAGEAPEE | PSVYATLAAA | RPEAVPKDME | Q

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.326531

SMR:

P97484

KEGG:

mmu:18733

Uniprot:

P97484

FOR

ELISA Kit for Mouse LIR-3

Cat.:

E9251h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Mouse LIR-3

Cat.:

E9251m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse LIR-3

Cat.:

U9251m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse LIR-3

Cat.:

U9251h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse LIR-3

Cat.:

P9251Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse LIR-3

Cat.:

P9251Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse LIR-3

Protein for Mouse LIR-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of a novel murine cell-surface glycoprotein homologous to killer cell inhibitory receptors."
Hayami K. , Fukuta D. , Nishikawa Y. , Yamashita Y. , Inui M. , Ohyama Y. , Hikida M. , Ohmori H. , Takai T.
J. Biol. Chem.272:7320-7327(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: B10.A.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1."
Blery M. , Kubagawa H. , Chen C.C. , Vely F. , Cooper M.D. , Vivier E.
Proc. Natl. Acad. Sci. U.S.A.95:2446-2451(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF TYR-794 AND TYR-824;INTERACTION WITH PTPN6/SHP-1 AND PTPN11/SHP-2;SUBCELLULAR LOCATION
4.

"Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1."
Maeda A. , Scharenberg A.M. , Tsukada S. , Bolen J.B. , Kinet J.P. , Kurosaki T.
Oncogene18:2291-2297(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION AT TYR-794 AND TYR-824 BY LYN;MUTAGENESIS OF TYR-794 AND TYR-824;INTERACTION WITH PTPN6/SHP-1 AND PTPN11/SHP-2;SUBCELLULAR LOCATION
5.

"Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B."
Ho L.H. , Uehara T. , Chen C.C. , Kubagawa H. , Cooper M.D.
Proc. Natl. Acad. Sci. U.S.A.96:15086-15090(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION BY LYN;INTERACTION WITH LYN AND PTPN6/SHP-1;TISSUE SPECIFICITY
6.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-684 AND SER-757;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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